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Web11 de abr. de 2024 · We consider two configurations for PanGenie: ‘high-gq’ filtering, where we use only genotypes reported with high quality scores and treat all other variants as not genotyped, and ‘all’, where... WebG-Quadruplex (GQ) nucleic acids are promising therapeutic targets in anticancer research due to their structural robustness, polymorphism, and gene-regulatory functions. Here, we presented the structure–activity relationship of carbazole-based monocyanine ligands using region-specific functionalization with benzothiazole (TCA and TCZ), lepidine (LCA and … ctfshow re2
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